イシカネ　ヒロシ   ISHIKANE Hiroshi   石金 浩史    所属   専修大学  人間科学部    専修大学大学院  文学研究科    職種   教授
発表年月日	2008/07
発表テーマ	Expression of SPIG1 reveals development of a functional subtype of ON direction selective ganglion cells in the mouse
会議名	Neuroscience 2008
主催者	Japan Neuroscience Society
学会区分	国際学会
開催地名	東京国際フォーラム,東京都千代田区
概要	概要 Our understanding about how visual pathways develop is still in its infancy, because few molecular markers corresponding to individual retinal ganglion cell (RGC) types are available. Here, we generated knock-in mice to visualize SPIG1-expressing cells with GFP. We found that the GFP (SPIG1) expression marks a functional subtype of ON direction selective ganglion cells (DSGCs) in a pan-ventronasal domain of the mouse retina during the neonatal period. Monitoring the GFP-labeled RGCs provided new insights into the developmental changes in the dendritic stratification and mosaic formation. SPIG1 will thus serve as a useful molecular marker for future studies on the development and function of ON DSGCs. 発表要旨集名Neuroscience 2008 発表要旨集名（英語）The 31st Annual Meeting of Japan Neuroscience Society Program 開始ページ163 終了ページ163 要旨集発刊年月200807