クメ　マナブ   Manabu Kume   久米　学    所属   石巻専修大学  理工学部    職種   准教授
言語種別	英語
発行・発表の年月	2009/10
形態種別	研究論文（学術雑誌）
査読	査読あり
標題	A role for a neo-sex chromosome in stickleback speciation
執筆形態	未選択
掲載誌名	Nature
出版社・発行元	NATURE PUBLISHING GROUP
巻・号・頁	461(7267),pp.1079-1083
著者・共著者	Jun Kitano,Joseph A. Ross,Seiichi Mori,Manabu Kume,Felicity C. Jones,Yingguang F. Chan,Devin M. Absher,Jane Grimwood,Jeremy Schmutz,Richard M. Myers,David M. Kingsley,Catherine L. Peichel
概要	Sexual antagonism, or conflict between the sexes, has been proposed as a driving force in both sex-chromosome turnover and speciation. Although closely related species often have different sex-chromosome systems, it is unknown whether sex-chromosome turnover contributes to the evolution of reproductive isolation between species. Here we show that a newly evolved sex chromosome contains genes that contribute to speciation in threespine stickleback fish (Gasterosteus aculeatus). We first identified a neo-sex chromosome system found only in one member of a sympatric species pair in Japan. We then performed genetic linkage mapping of male-specific traits important for reproductive isolation between the Japanese species pair. The neo-X chromosome contains loci for male courtship display traits that contribute to behavioural isolation, whereas the ancestral X chromosome contains loci for both behavioural isolation and hybrid male sterility. Our work not only provides strong evidence for a large X-effect on reproductive isolation in a vertebrate system, but also provides direct evidence that a young neo-X chromosome contributes to reproductive isolation between closely related species. Our data indicate that sex-chromosome turnover might have a greater role in speciation than was previously appreciated.